Open Positions

In this role the Research Associate will support biology as a member of a highly matrixed drug discovery team and will be responsible for the execution and troubleshooting of various cell-based and biochemical assays and experiments.  The Research Associate will contribute to drug screening and mechanism-of-action studies for projects in immuno-oncology and neurological diseases and disorders and have opportunities to contribute to new target discovery and validation.  This proactive researcher will collaborate with team members, identify opportunities to improve efficiency, share ideas and expertise and contribute to Axial’s creative, dynamic, and collaborative culture.

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Responsibilities:

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• Provide critical laboratory support while working as part of an energetic, collaborative team

• Assist with the optimization and validation of cell-based or biochemical assays to support ongoing discovery projects

• Use cellular or biochemical assays to characterize small molecules and biologics that modulate pathways relevant to cancer, immunology and neurological diseases and disorders

• Analyze and report data to multidisciplinary teams of scientists internally

• Maintain excellent and detailed records in an electronic notebook

• Prepare laboratory reagents and order supplies and equipment

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Qualifications

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• Careful, thoughtful, and collegial bench scientist with experience and proficiency with a variety of molecular and cell biology techniques such as cell culture, Westerns or ELISA, PCR, transfections or transformations, and protein purification

• Strong scientific curiosity, ability to rapidly learn new laboratory and data analysis methods

• Self-starter with strong problem-solving abilities and resourcefulness, and an outstanding team player with ability to work in groups as well as independently

• Highly detail-oriented and organized with strong analytical skills

• Ability to multitask, prioritize, and function in a fast-paced, entrepreneurial environment

• Bachelor’s degree in biology, biochemistry, or a related field preferred, with at least 1-3 years of relevant lab experience

• Experience supporting drug discovery programs preferred

 

About Axial

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As the scientific leader in the biological role of the microbiome gut-brain axis and its impact on neurological conditions, Axial Therapeutics is uniquely positioned to advance a fundamentally different therapeutic approach for the treatment of neurological diseases and disorders. We stand apart through our focus on the microbiome, harnessing our expertise to identify new drug targets in the gut and develop novel medical interventions that have significant potential for improving symptoms and treating underlying disease.

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Our focus on the microbiome gut-brain axis is a transformational shift from traditional approaches to treating neurological conditions. By identifying bacteria and their products in the gut that are linked to the pathology, progression, and symptoms of neurodegenerative diseases and neurodevelopmental disorders, we can validate “druggable” therapeutic targets in the gut microbiome. Based on these new classes of targets, we focus on developing small molecule therapies with defined mechanisms of action that mitigate the impact of bacteria and their products. Our localized, gut-targeted small molecule approach represents an evolution in microbiome-inspired therapeutics for neurological conditions.